The Arizona Diamondbacks handed the Houston Astros a gut-punch 4-3 defeat in 10 innings at Minute Maid Park on Saturday, September 5, 2026, overcoming a two-run deficit to escape with a one-run win. Isaac Paredes delivered a gutsy 2-for-5 night with three RBI to keep Houston in it, but Bryan King surrendered the decisive run in the 10th and the bullpen couldn't hold what the offense had built. Jonathan Loáisiga picked up the win for Arizona; Brandyn Garcia locked it down with a two-strikeout save in the final frame.

Isaac Paredes Carries the Offense, But It Isn't Enough

Paredes was the engine for Houston on Saturday. He went 2-for-5 and drove in all three of the Astros' runs, accounting for every RBI Houston put on the board. Yainer Diaz went 2-for-4 and Cam Smith added a 2-for-4 performance of his own, giving the Astros three multi-hit contributors in the lineup. The problem wasn't generating contact — it was running out of answers when Arizona answered back.

Brandon Pfaadt started for the Diamondbacks and allowed those three earned runs on seven hits and two walks across 6.1 innings, striking out four. He gave Arizona enough length to hand the ball to their bullpen with a lead they'd clawed back, and Kevin Ginkel, Juan Morillo, Loáisiga, and Garcia finished the job without allowing another run.

Houston's Bullpen Falters in the 10th

The Astros got strong work out of Enyel De Los Santos, who tossed 1.2 scoreless innings on zero hits and two strikeouts. Josh Hader worked a clean ninth — one strikeout, no hits, no runs — which set up what looked like a potential extra-inning opportunity for Houston to win it. Instead, the 10th unraveled.

Kai-Wei Teng struggled badly in his 0.1-inning appearance, allowing one earned run on two walks and striking out one before exiting. AJ Blubaugh came on and went 1.2 innings with two strikeouts but also allowed two earned runs on two hits. King finished out the game and was charged with the loss after Arizona pushed the winning run across.

Starter Ethan Pecko had given Houston a workable outing earlier — 4.1 innings, one earned run, five hits, two strikeouts, one walk — but the bullpen arms behind him couldn't maintain the margin when it mattered most.

Arizona's Comeback — and the Turning Point

The Diamondbacks came into the 10th trailing and turned it around. The verified game metadata confirms Arizona overcame a two-run deficit to win, making this a genuine comeback victory for the visiting club. Ketel Marte went 1-for-5 with a home run and one RBI. Lars Nootbaar went 2-for-3 with an RBI, and Gabriel Moreno contributed a 2-for-5, one-RBI evening to support the Arizona charge.

The turning point was the 10th inning itself — Teng's two walks opened the door and Arizona walked through it. Once King inherited the situation, Houston never recovered.

Key Performances at a Glance

Houston Astros

  • Isaac Paredes: 2-for-5, 3 RBI
  • Yainer Diaz: 2-for-4
  • Cam Smith: 2-for-4
  • Enyel De Los Santos: 1.2 IP, 0 ER, 0 H, 2 K
  • Josh Hader: 1.0 IP, 0 ER, 0 H, 1 K

Arizona Diamondbacks

  • Ketel Marte: 1-for-5, 1 HR, 1 RBI
  • Lars Nootbaar: 2-for-3, 1 RBI
  • Gabriel Moreno: 2-for-5, 1 RBI
  • Jonathan Loáisiga (W): 1.0 IP, 0 ER, 1 H, 2 K
  • Brandyn Garcia (SV): 1.0 IP, 0 ER, 0 H, 2 K

What's Next for the Astros

Houston drops this one at home and will need to respond. The offense showed enough life — three multi-hit performances and a three-RBI game from Paredes — to feel like the bats weren't the core issue on Saturday. The bullpen's 10th-inning implosion is the story that will linger. The Astros will look to bounce back as this series with Arizona continues at Minute Maid Park.